Comments on: Fats and Insulin Resistance http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/ the diet written by evolution itself Mon, 16 Nov 2009 21:57:21 +0000 http://wordpress.com/ hourly 1 By: Living in La La Land « At Darwin’s Table http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-953 Living in La La Land « At Darwin’s Table Mon, 30 Mar 2009 07:37:58 +0000 http://darwinstable.wordpress.com/?p=1397#comment-953 [...] I might also watch the saturated fat intake too since this has also been associated with increased insulin resistance. I know that this is a controversial comment but at the moment Im not taking any risks. Also, Im [...] [...] I might also watch the saturated fat intake too since this has also been associated with increased insulin resistance. I know that this is a controversial comment but at the moment Im not taking any risks. Also, Im [...]

]]> By: Dr Dan http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-820 Dr Dan Wed, 11 Mar 2009 07:36:46 +0000 http://darwinstable.wordpress.com/?p=1397#comment-820 I thought you mean't saturated fats. Thanks for the info. I thought you mean’t saturated fats. Thanks for the info.

]]> By: Steve Parker, M.D. http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-818 Steve Parker, M.D. Wed, 11 Mar 2009 06:38:30 +0000 http://darwinstable.wordpress.com/?p=1397#comment-818 Referring to Vessby's article of 2001, I wrote above that: "Lp(a) [lipoprotein(a)] rose by 12% in the monounsaturated fat diet, compared to the unsaturated fat diet (no change). Lp(a) is a risk factor for atherosclerotic complications." I meant to write, "Lp(a) rose by 12% in the monounsaturated fat diet, compared to the SATURATED fat diet (no change)." Vessby's saturated fat diet was described as including butter and a table margarine containing a relatively high proportion of saturated fatty acids. In contrast, the monounsaturated fat diet used a spread and margarine containing high proportions of oleic acid derived from high-oleic sunflower oil. You know, but your readers may not, that the main monounsaturated fat in olive oil is oleic acid. I'm sorry to obfuscate an inherently confusing topic! -Steve Referring to Vessby’s article of 2001, I wrote above that:

“Lp(a) [lipoprotein(a)] rose by 12% in the monounsaturated fat diet, compared to the unsaturated fat diet (no change). Lp(a) is a risk factor for atherosclerotic complications.”

I meant to write, “Lp(a) rose by 12% in the monounsaturated fat diet, compared to the SATURATED fat diet (no change).”

Vessby’s saturated fat diet was described as including butter and a table margarine containing a relatively high proportion of saturated fatty acids. In contrast, the monounsaturated fat diet used a spread and margarine containing high proportions of oleic acid derived from high-oleic sunflower oil.

You know, but your readers may not, that the main monounsaturated fat in olive oil is oleic acid.

I’m sorry to obfuscate an inherently confusing topic!

-Steve

]]> By: Dr Dan http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-815 Dr Dan Tue, 10 Mar 2009 21:22:26 +0000 http://darwinstable.wordpress.com/?p=1397#comment-815 SoG - yes thats what I thought too!!! I might amend it because I think thats important. Steve - your right it is a bit of a leap to say sunflower oil works and therefore this must be true for monounsaturated fats. Then again its kind of backed up by the animal studies and shows the same thing so it does have some credibility. Also to clarify Lp(a) rose in monounsturated vs unsaturated? By unsaturated did you mean polyunsaturated or did you mean saturated. SoG – yes thats what I thought too!!! I might amend it because I think thats important.

Steve – your right it is a bit of a leap to say sunflower oil works and therefore this must be true for monounsaturated fats. Then again its kind of backed up by the animal studies and shows the same thing so it does have some credibility. Also to clarify Lp(a) rose in monounsturated vs unsaturated? By unsaturated did you mean polyunsaturated or did you mean saturated.

]]> By: Steve Parker, M.D. http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-814 Steve Parker, M.D. Tue, 10 Mar 2009 19:47:15 +0000 http://darwinstable.wordpress.com/?p=1397#comment-814 Thanks for publishing this. The 2001 human study by Vessby et al is very helpful to me since I deal with humans. The monounsaturated fats in that study were predominantly from high-oleic sunflower oil. Olive oil was negligible by design. The study authors don't discuss whether the observed metabolic changes apply only to sunflower oil or not. The implication is that all sources of monounsaturated fats would have the same effects - which may or may not be true. (I haven't tried to find out.) Lp(a) [lipoprotein(a)] rose by 12% in the monounsaturated fat diet, compared to the unsaturated fat diet (no change). Lp(a) is a risk factor for atherosclerotic complications. So maybe you shouldn't fee too bad about your high saturated fat intake. I'll be looking for similar studies in people with metabolic syndrome, prediabetes, and diabetes.. -Steve The Vessby study food was supplied by several food manufacturers, with additional support from the International Council of Olive Oil and others. Nothing necessarily wrong with that. Thanks for publishing this.

The 2001 human study by Vessby et al is very helpful to me since I deal with humans. The monounsaturated fats in that study were predominantly from high-oleic sunflower oil. Olive oil was negligible by design. The study authors don’t discuss whether the observed metabolic changes apply only to sunflower oil or not. The implication is that all sources of monounsaturated fats would have the same effects – which may or may not be true. (I haven’t tried to find out.)

Lp(a) [lipoprotein(a)] rose by 12% in the monounsaturated fat diet, compared to the unsaturated fat diet (no change). Lp(a) is a risk factor for atherosclerotic complications.

So maybe you shouldn’t fee too bad about your high saturated fat intake.

I’ll be looking for similar studies in people with metabolic syndrome, prediabetes, and diabetes..

-Steve

The Vessby study food was supplied by several food manufacturers, with additional support from the International Council of Olive Oil and others. Nothing necessarily wrong with that.

]]> By: Son of Grok http://darwinstable.wordpress.com/2009/03/10/fats-and-insulin-resistance/#comment-813 Son of Grok Tue, 10 Mar 2009 14:38:35 +0000 http://darwinstable.wordpress.com/?p=1397#comment-813 Another way to look at this might be to point out that if consuming a diet high in fat it is extremely important to keep insulin resistance down by moderating sugar and carbohydtrate intake. This may be why the high fat/ low carb diet works. In a typical western diet of high fat/high carbohydrate... this sounds like a recipe for disaster. The SoG Another way to look at this might be to point out that if consuming a diet high in fat it is extremely important to keep insulin resistance down by moderating sugar and carbohydtrate intake. This may be why the high fat/ low carb diet works. In a typical western diet of high fat/high carbohydrate… this sounds like a recipe for disaster.

The SoG

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